{"id":1304,"date":"2025-02-26T22:04:20","date_gmt":"2025-02-26T22:04:20","guid":{"rendered":"https:\/\/content.scienceofecd.com\/transcript\/?page_id=1304"},"modified":"2025-02-26T22:04:20","modified_gmt":"2025-02-26T22:04:20","slug":"transcript-kobor-epigenetic-examples-in-the-early-years","status":"publish","type":"page","link":"https:\/\/content.scienceofecd.com\/transcript\/transcript-kobor-epigenetic-examples-in-the-early-years\/","title":{"rendered":"Transcript Kobor \u2013 epigenetic examples in the early years"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">We have shown for example things like in our most recent work we have shown that it\u2019s the parental stress that kids are exposed to, and it\u2019s actually quite interesting in this particular work that we just recently published in collaboration with folks at the University of Wisconsin, and here at UBC, that actually it\u2019s quite distinct, so it seems like the stress of the mother affects these dimmer switches in infancy. In contrast, the stress of the father affects these dimmer switches during the preschool period, and even more specifically, it only affects it in the girls, versus the mom\u2019s stress affects both girls and boys, so that\u2019s quite remarkable, and it fits very well with what people know about the interplay of parental influences and kids\u2019 behaviour during these developmental periods. We\u2019ve also shown, and others have shown that as well, for example, early life socio-economic starters can tweak with those dimmer switches. So for example, if you grow up in a low socio-economic status environment for the first five years of life, we can see that 20-30 years later in those dimmer switches in that they are set in a way you\u2019re more likely to have inflammation and things like that in your system. That in turn, we actually also found reassuringly, that can be buffered up to some extent by maternal warmth. So it\u2019s this kind of social environment. if you will. which can set these dimmer switches. There\u2019s work out there that physical environment, certain chemicals in the environment can set these dimmer switches, so I think it\u2019s very early days for this research, and I\u2019m looking forward over the next few years to have a much broader catalogue of influences that can set these dimmer switches and also perhaps to understand whether there are particularly sensitive periods. We always think that the early years are very sensitive, there\u2019s certainly evidence for this, but we haven\u2019t really tested, in a longitudinal fashion, how that actually develops over, say, the course of childhood.&nbsp;&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>We have shown for example things like in our most recent work we have shown that it\u2019s the parental stress that kids are exposed to, and it\u2019s actually quite interesting in this particular work that we just recently published in collaboration with folks at the University of Wisconsin, and here at UBC, that actually it\u2019s [&hellip;]<\/p>\n","protected":false},"author":39,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-text-only.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-1304","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/content.scienceofecd.com\/transcript\/wp-json\/wp\/v2\/pages\/1304","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/content.scienceofecd.com\/transcript\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/content.scienceofecd.com\/transcript\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/content.scienceofecd.com\/transcript\/wp-json\/wp\/v2\/users\/39"}],"replies":[{"embeddable":true,"href":"https:\/\/content.scienceofecd.com\/transcript\/wp-json\/wp\/v2\/comments?post=1304"}],"version-history":[{"count":1,"href":"https:\/\/content.scienceofecd.com\/transcript\/wp-json\/wp\/v2\/pages\/1304\/revisions"}],"predecessor-version":[{"id":1305,"href":"https:\/\/content.scienceofecd.com\/transcript\/wp-json\/wp\/v2\/pages\/1304\/revisions\/1305"}],"wp:attachment":[{"href":"https:\/\/content.scienceofecd.com\/transcript\/wp-json\/wp\/v2\/media?parent=1304"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}